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Cardiovascular Tissue Engineering

CVET develops engineered cardiovascular tissues and biomaterial-based constructs to restore, replace, and model cardiac and vascular function. By integrating cells, biomaterials, mechanics, and biofabrication, we aim to create living systems that promote regeneration, improve tissue integration, and provide more physiologically relevant platforms for cardiovascular research. 
An image showing microtubule structure (green) in an adult cardiomyocyte (nucleus shown in red).

Engineered Cardiac Tissues

CVET develops human cardiac tissues to study myocardial structure, electrophysiology, contractile function, and response to injury or treatment. These platforms can support both regenerative strategies and human-relevant testing of cardiovascular therapies and technologies. 

Tissue-Engineered Vascular Grafts

CVET develops tissue-engineered vascular grafts designed to restore blood flow while promoting functional integration and long-term remodeling. Research focuses on biomaterial design, vascular-cell interactions, endothelialization, smooth-muscle regeneration, mechanical performance, and the host response to implantation. These grafts also provide a platform for studying how materials, cells, and therapeutic signals can be combined to create living vascular replacements. 
A bright microscopic image of a vascular graft