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Cardiovascular Disease Models and Testing Platforms

CVET develops human-relevant, computational, and preclinical models to investigate cardiovascular disease and evaluate new devices, imaging technologies, and therapeutics. These platforms connect fundamental biology with engineering development by enabling controlled studies of disease mechanisms, treatment response, and translational performance across cardiac and vascular systems. 

Human Cardiac Models

CVET uses human cardiac tissues and cell-based systems to study electrophysiology, contractile function, metabolism, and treatment response. Current platforms include living human cardiac slices, patient-derived cells, and iPSC-derived cardiomyocytes, providing clinically relevant tools for investigating arrhythmia, heart failure, cardiotoxicity, and other forms of cardiac injury. 

Cardiovascular Disease Models

CVET integrates genomic, transcriptomic, imaging, and physiological data to identify disease mechanisms, therapeutic targets, and predictors of treatment response. Computational analysis and standardized testing platforms support comparison of technologies across models and help guide progression from early discovery to preclinical validation.